产品描述General descriptionIrreversible inhibitor of serine proteases. Its mechanism of action is analogous to that of diisopropylfluorophosphate. PMSF causes sulfonylation of the active-site serine residues. Also reported to inhibit internucleosomal DNA fragmentation in immature thymocytes. Effective at a concentration of 50 µM.
Irreversible inhibitor of serine proteases. Its mechanism of action is analogous to that of diisopropylfluorophosphate. PMSF causes sulfonylation of the active-site serine residues. Also reported to inhibit internucleosomal DNA fragmentation in immature thymocytes. For a related, more stable inhibitor, see AEBSF (Cat. No. 101500 包装1 g in Alu drum 5 g in Glass bottle 25 g in Fibre case Biochem/physiol ActionsCell permeable: no
Primary Target Product does not compete with ATP. Reversible: no WarningToxicity: Corrosive (L) ReconstitutionFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 9 months at 4°C. t½ = 1 hour at pH 7.5. Effective concentration: 50 μM. Other NotesDue to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Seitz, R., et al. 1993. Int. J. Cancer53, 514. 法律信息CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
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